王文静

发布时间:2020-11-27 浏览次数:

 

基本信息

姓名:王文静

出生年月:19901

民族:汉族

邮箱:wangwj0122@163.com

 

教育及工作经历

2020.10—至今  中南民族大学药学院,讲师

2018.6—2020.5  华中科技大学药学院,博士后(合作导师: 张勇慧教授

2015.9—2018.9  华中科技大学药学院,医学博士(导师:张勇慧教授)

2012.9—2015.6  沈阳药科大学,理学硕士

2008.9—2012.6  湖北中医药大学,理学学士

 

研究方向

1.微生物次生代谢产物化学结构及生物活性研究

2.微生物天然产物生物合成研究

 

科研项目
1.石蒜内生菌简青霉次生代谢产物及其生物活性研究31900288),国家自然科学基金青年项目,2020.01-2022.1224万元,主持,在研。

2.简青霉次生代谢产物及其生物活性研究2019M652660,中国博士后科学基金面上项目,2019.01-2020.128万元,主持,已结题。

3.灰黄青霉吲哚生物碱次生代谢产物及其免疫抑制活性研究(31800285),国家自然科学基金青年项目,2019.01-2021.1224万元,参与,在研。

4.Aspergillus micronesiensis中新颖杂聚细胞松弛素的发现及其活性研究(21772048),国家自然科学基金面上项目,2018.01-2022.1266万元,参与,在研。

 

代表性论文

(1) Wenjing Wang, Fanrong Zeng, Qiong Bie, Chong Dai,Chunmei Chen, Qingyi Tong, Junjun Liu, Jianping Wang, Yuan Zhou, Hucheng Zhu(*), Yonghui Zhang(*), Cytochathiazines A−C: Three Merocytochalasans with a 2H-1,4-Thiazine Functionality from Coculture of Chaetomium globosum and Aspergillus flavipes, Organic Letters, 2018, 20, 6817-6821.

(2)  Wenjing Wang, Jiaojiao Gong, Xiaorui Liu, Chong Dai, Yanyan Wang, Xiaonian Li, Jianping Wang, Zengwei Luo, Yuan Zhou, Yongbo Xue, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Cytochalasans produced by the co-culture of Aspergillus flavipes and Chaetomium globosum, Journal of Natural Products, 2018, 81, 1578–1587.

(3) Wenjing Wang, Xiao Wan, Junjun Liu, Jianping Wang, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Two New Terpenoids from Talaromyces purpurogenus, Marine Drugs, 2018,16, 150. 

(4) Wen-Jing Wang, Dan-Yi Li, Yan-Chun Li, Hui-Ming Hua, En-Long Ma(*), Zhan-Lin Li(*). Caryophyllene Sesquiterpenes from the Marine-Derived Fungus Ascotricha sp. ZJ-M 5 by the One Strain-Many Compounds Strategy. Journal of Natural Products, 2014, 77, 1367–1371. 

(5) Wenjing Wang, Chong Dai, Jianping Wang, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae, Current Medical Science, 2020, 40, 232–238.

(6) Chong Dai(#), Chunmei Chen(#), Danyingzi Guan, Hailun Chen, Fuxin Wang, Wenjing Wang, et al., Yonghui Zhang(*), Pesimquinolones produced by Penicillium simplicissimum and their inhibitory activity on nitric oxide production, Phytochemisy, 2020, 174, 112327.

(7) Xiaotian Zhang(#), Lu Yang(#), Wenjing Wang, et al., Yonghui Zhang(*), Flavipesines A and B and Asperchalasines E−H: Cytochalasans and Merocytochalasans from Aspergillus flavipes, Journal of Natural Products, 2019, 82, 2994-3001.

(8) Fanrong Zeng(#), Chunmei Chen(#), Ali Adhab AL Chnani, Qun Zhou, Qingyi Tong, Wenjing Wang, Yi Zang, Jiaojiao Gong, Zhaodi Wu, Junjun Liu, Jianping Wang, Hucheng Zhu(*), and Yonghui Zhang(*), Dibrefeldins A and B, A Pair of Epimers Representing the First Brefeldin A Dimers with cytotoxic activities from Penicillium janthinellum, Bioorganic Chemistry, 2019, 86, 176-182.

(9) Jiaojiao Gong, Chunmei Chen, Shuyuan Mo, Junjun Liu, Wenjing Wang, Yi Zang, Huaqiang Li, Chenwei Chai, Hucheng Zhu, Zhengxi Hu*, Jianping Wang*, Yonghui Zhang*. Fusaresters A–E, new γ-pyrone-containing polyketides from fungus Fusarium sp. Hungcl and structure revision of fusariumin D. Organic & Biomolecular Chemistry. 2019, 17, 5526−5532.

(10) Shupeng Zou(#), Zhongbo Wang(#), Jing Wang(#), Guangzheng Wei, Wenjing Wang, Yi Zang, Fanrong Zeng, Keliang Chen, Junjun Liu, Jianping Wang, Zengwei Luo, Yongbo Xue, Hucheng Zhu, Chunping Yin(*), Chunmei Chen(*), and Yonghui Zhang(*), Azacoccones A−E, Five Unexpected Aza-epicoccone Derivatives from Aspergillus flavipes, 2018, Fitoterapia, 124, 127–131.

(11) Guangzheng Wei(#), Chunmei Chen(#), Qingyi Tong(#), Jinfeng Huang, Wenjing Wang, Zhaodi Wu, Jing Yang, Junjun Liu, Yongbo Xue, Zengwei Luo, Jianping Wang, Hucheng Zhu(*), and Yonghui Zhang(*), Aspergilasines A–D: four merocytochalasans with new carbon skeletons from Aspergillus flavipes QCS12, Organic Letters, 2017, 19, 4399−4402.

(12) Jin-Ling Zhang, Wen-Jing Wang, Xiu-Mei Xu, Dan-Yi Li, Hui-Ming Hua, En-Long Ma(*), Zhan-Lin Li(*). From macrocyclic to linear and further: naturally degradable polyesters from the fungus Ascotricha sp. ZJ-M-5. Tetrahedron, 2016, 72, 4895–4901.

(13) Hong-Jie Shang, Dan-Yi Li, Wen-Jing Wang, Zhan-Lin Li(*), Hui-Ming Hua(*), Three new diterpenoids from the resin of Liquidambar formosana, Natural Products Research, 2014, 28, 1–6.

 

 

 

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