艾洪莲

发布时间:2019-10-17 浏览次数:


艾洪莲

出生年月:19813

民族:汉

职称:副教授硕士生导师

电子邮箱:aihonglian05@163.com

 历:

2019--至今,中南民族大学,药学院,副教授

2015/07-2018/12,中南民族大学,药学院,讲师

2010/082015/07,云南农业大学,农学与生物技术学院,讲师

2005/092010/07,中国科学院昆明植物研究所,植物学,博士

研究方向:民族药用植物内生真菌及其次生代谢产物研究

主持国家自然科学基金2项,中央高校专项资金项目4项,横向课题2项,参与国家自然科学基金11项,出版专著2部,以第一作者或者共同通讯作者发表研究论文40篇,包括包括Organic Letters, J. Nat. Prod., BMC Plant Biology, RSC Advances, Fitoterapia, Chemistry & Biodiversity, Phytochemistry Letters, Natural Product Research, Ecotoxicology and Environmental SafetyFish & Shellfish Immunology, Journal of Asian Natural Products Research,, Natural Products & Bioprospecting等,申请专利2项。

主持科研项目

1.国家自然科学基金青年科学基金项目,32000011,《马铃薯内生真菌单端孢与马铃薯病原真菌相互作用的化学防御性成分研究》,2021/01-2023/1224万元,在研。主持

2.国家自然科学基金地区项目,31560010,《马铃薯内生真菌次生代谢产物研究及活性评价》,2016/01-2019/1248万元,已结题。主持

3.横向课题,HZY16004,《重要野生植物种质资源的采集和保存》,2016/01-2017/125.0万,结题。主持

4.横向课题,HZY17019,《华中地区野生植物种质资源的采集和保存》,2017/06-2018/1210.0万,在研。主持

5.中央高校基本科研业务费专项资金项目,CZP17094,《黄精高产栽培技术及炮制过程中化学成分变化对其抗糖尿病活性的影响》,2017/05-2017/125.0万,结题。主持

6.中央高校基本科研业务费专项资金项目, CSP17067,《恩施州野生民族药材种质资源及产业化调研》,2017/07-2017/122.5万,结题。主持

7.中央高校基本科研业务费专项资金项目,CZH18001,《中国少数民族医药资源发掘与保护研究傣医药》,2018/01-2019/124.0万,结题。主持

代表性研究成果

1. Ye Ke, Hong-Lian Ai*, Ji-Kai Liu. Identification and Bioactivities of Secondary Metabolites Derived from Endophytic Fungi Isolated from Ethnomedicinal Plants of Tujia in Hubei Province: A Review. Nat. Prod. Bioprospect. (2021). https://doi.org/10.1007/s13659-020-00295-5.

2. Hui-Xiang Yang#, Xing Wu#, Mei-Jing Chi, Zheng-Hui Li, Tao Feng, Hong-Lian Ai*, and Ji-Kai Liu*. Structure and cytotoxicity of trichothecenes produced by the potato-associated fungus Trichothecium crotocinigenum. Bioorganic Chemistry. 2021, 111: 104874.

3. Yao Chen, Li-Tang Sun, Hui-Xiang Yang, Zheng-Hui Li, Ji-Kai Liu, Hong-Lian Ai,

Guo-Kai Wang, Tao Feng. Depsidones and diaryl ethers from potato endophytic fungus Boeremia exigua. Fitoterapia, 2020, 141, 104483.

4. Hui-Xiang Yang#, Juan He#, Fa-Lei Zhang, Xian-Dong Zhang, Zheng-Hui Li, Tao Feng*, Hong-Lian Ai*, and Ji-Kai Liu*. Trichothecrotocins D−L, Antifungal Agents from a Potato-Associated Trichothecium crotocinigenum. Journal of Natural Products. 2020, 83(9): 2756–2763.

5. Hong-Lian Ai, Chun-Lun Qin, Ke Ye, Zheng-Hui Li. Characterization of the complete chloroplast genome of a well-known Chinese medicinal herb, Scrophularia ningpoensis. Mitochondrial DNA Part B Resources. 2020, 5(1): 484-485.

6. Hong-Lian Ai, Xiao Lv, Ke Ye, Xian Zhang, Li-Yun Zhou, Zheng-Hui Li. The complete chloroplast genome of a well-known medicinal herb, Senna tora. Mitochondrial DNA Part B Resources. 2020, 5(2): 1659-1660.

7. Xian Zhang, Fa-Lei Zhang, Xing Wu, Ke Ye, Xiao Lv, Hong-Lian Ai*, Ji-Kai Liu*. Bioactive Polyketides From the Potato Endophytic Fungus Aspergillus carneus. Natural Product Communications. 2020, 15(12): 1-5.

8. Wen-Xuan Wang, Xinxiang Lei, Hong-Lian Ai*, Xue Bai, Jing Li, Juan He, Zheng-Hui Li, Yong-Sheng Zheng, Tao Feng*, Ji-Kai Liu*. Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans. Organic Letters, 2019, 21: 1108-1111.

9. Wen-Xuan Wang, Zheng-Hui Li, Hong-Lian Ai*, Jing Li, Juan He, Yong-Sheng Zheng, Tao Feng*, Ji-Kai Liu*. Cytotoxic 19,20-epoxycytochalasans from endophytic fungus Xylaria cf. curta. Fitoterapia, 2019, 137, 104253.

10. Juan He, Man-Si Yang, Wen-Xiang Wang, Zheng-Hui Li, Waill Ahmed Mohamed Elkhateeb, Ting-Chi Wen*, Hong-Lian Ai*, Tao Feng*. Anti-phytopathogenic sesquiterpenoid-xanthone adducts from potato endophytic fungus Bipolaris eleusines. RSC Advances, 2019, 9: 128-131.

11. Wenxiang Wang, Xilatu Dabu, Juan He, Huixiang Yang, Shengchao Yang, Junwen Chen, Wei Fan, Guanghui Zhang, Jinlong Cai, Honglian Ai*, Meirong Hai*. Polygonatone H, a new homoisoflavanone with cytotoxicity from Polygonatum Cyrtonema Hua. Natural Product Research, 2019, 33(12): 1727-1733. (SCI IF=1.9

12. Wen-Xuan Wang#, Mei-Jia Zheng#, Jing Li, Tao Feng, Zheng-Hui Li, Rong Huang, Yong-Sheng Zheng, Huan Sun, Hong-Lian Ai*, Ji-Kai Liu*. Cytotoxic polyketides from endophytic fungus Phoma bellidis harbored in Ttricyrtis maculate. Phytochemistry Letters, 2019, 29: 41-46.

13. Wen-Xiang Wang#, Xian Zhang#, Xi-La-Tu Dabu, Juan He, Sheng-Chao Yang, Jun-Wen Chen, Wei Fan, Guang-Hui Zhang, Hong-Lian Ai*, Mei-Rong Hai*, Analysis of chemical constituents from Polygonatum cyrtonema after “Nine-Steam-Nine-Bask”processing. Phytochemistry Letters, 2019, 29: 35-40.

14. Wen-Xuan Wang, Tao Feng, Zheng-Hui Li, Jing Li, Hong-Lian Ai, Ji-Kai Liu. Cytochalasins D1 and C1, unique cytochalasans from endophytic fungus Xylaria cf. curta. Tetrahedron Letters, 2019, 60:150952.

15. Zheng-Hui Li#, Xue Bai#, Jiao-Xian Du, Jia-Yi Li, Juan He, Hong-Lian Ai*. Zingiberols A‒C, three rare diterpenols and their cytotoxicities from Zingiber mioga. Phytochemistry Letters, 2019, 33: 106-109.

16. Ling-sheng Bao, Yuan-hua Chen, Hong-hui Li, Jian-she Zhang, Ping Wu, KeYe, Hong-lian Ai*, Wu-ying Chu*. Dietary Ginkgo biloba leaf extract alters immune-related gene expression and disease resistance to Aeromonas hydrophila in common carp Cyprinus carpio. Fish & Shellfish Immunology. 2019, 94: 810-818.

17. Zheng-Hui Li, Ke Ye, Xiao Lv, Xian Zhang, Li-Zhen Ling, Hong-Lian Ai*, Shu-Dong Zhang*. Characterization of the complete chloroplast genome of Paederia scandens (Rubiaceae): a Chinese folk medicinal plant. Mitochondrial DNA Part B Resources. 2019,4(2): 4075-4076.

28. Hong-Lian Ai, Ke Ye, Xian Zhang, Xiao Lv, Zheng-Hui Li*, Shu-Dong Zhang*. The complete plastid genome of Iris domestica: a traditional Chinese medicine. Mitochondrial DNA Part B Resources. 2019,4(2): 4214-4215.

19. Wen-Xuan Wang, Zheng-Hui Li, Tao Feng, Jing Li, Huan Sun, Rong Huang, Qing-Xia Yuan, Hong-Lian Ai*, Ji-Kai Liu*. Curtachalasins A and B, Two Cytochalasans with a Tetracyclic Skeleton from the Endophytic Fungus Xylaria curta E10. Organic Letters, 2018, 20: 7758-7761.

20. Hui-Xiang Yang#, Hong-Lian Ai#, Tao Feng*, Wen-Xuan Wang, Bin Wu, Yong-Sheng Zheng, Huan Sun, Juan He, Zheng-Hui Li, Ji-Kai Liu*. Trichothecrotocins A-C, Anti-phytopathogenic Agents from Potato Endophytic Fungus Trichothecium crotocinigenum., Organic Letters, 2018, 20: 8069-8072.

21. Huihui Zhu#, Honglian Ai#, Liwen Cao, Ran Sui, Hengpeng Ye, Dongyun Du, Jie Sun, Jun Yao, Ke Chen*, Liang Chen* . Transcriptome analysis providing novel insights for Cd-resistant tall fescue responses to Cd stress. Ecotoxicology and Environmental Safety, 2018, 160, 349-356.Dongyun Du, Liang Chen. Nitric oxide alleviates toxicity of hexavalent chromium on tall fescue and improves performance of photosystem II. Ecotoxicology and Environmental Safety, 2018, 164, 32-40.

著作

1. 刘琴,赵大克,艾洪莲.《傣医药》,武汉,湖北科学技术出版社,2018. 05。(450千字)

2.艾洪莲.《湖北土家族常用药用植物彩色图鉴(抗风湿及跌打损伤类)》,武汉,湖北科学技术出版社,2020.10.


申请专利

1. 艾洪莲, 何隽,邵倩 黄精化合物的应用及制备方法、减脂减肥食品及药物. 专利号:ZL201810125885.6    国家知识产权局

2. 艾洪莲, 王文宣, 张娴, 冯涛, 何隽, 李正辉 化合物E1011及其制备方法与应用、马铃薯内生真菌的发酵产物及其乙酸乙酯萃取液. 专利号: ZL201811112609.2.  国家知识产权局

所获荣誉

2020-2021年度五四青年(教工)先锋;

中南民族大学药学院优秀班主任

中南民族大学暑期三下乡优秀指导老师

中南民族大学寒假社会实践活动优秀指导老师

中南民族大学创新项目优秀指导教师

中南民族大学挑战杯”“优秀指导老师

校级十佳班主任、多次获校级优秀班主任(云南农大)。



地址:中国-湖北-武汉 民族大道182号中南民族大学药学院 邮编:430074
电话:027-67841196  Fax: 027-67841196
© 2016 中南民族大学药学院