出生年月：1994年8月
民族：汉族
职称：讲师
学科专业：基础医学、药理学、药物毒理学、民族药学
研究方向：民族药治疗代谢性疾病的作用及机制研究
电子邮箱：chenhuijian826@mail.scuec.edu.cn
教育经历
2012.9-2016.6 武汉工程大学化工与制药学院药物制剂 工学学士
2016.9-2022.6 武汉大学 基础医学院 基础医学（药物毒理学） 医学博士
工作经历
2022.6-2025.6 中南民族大学 药学院 预备师资
2026.5-至今 中南民族大学 药学院 讲师
教学方面
承担《药理学》、《病理学》、《细胞生物学实验》、《人体解剖生理学实验》、《生药学实验》等课程
2025年12月获湖北省/武汉药理学会学术会议教师教学竞赛二等奖
参与2019年全国医学专业学位研究生教指委研究课题；
参与2016年湖北省级教学改革课题
发表教学论文：陈慧剑,张晚霞,张郦,曾汉高,谢先飞,鄢友娥.医学生创新能力评价方法优化及对教学的指导作用[J].数理医药学杂志，2018,31:313-316.
科研项目
1.国家自然科学基金青年项目，藏药“甲蒂”口山酮类化合物介导ABCA1与整合素间信息交流治疗2型糖尿病的作用及机制，30万元，主持
2.湖北省自然科学基金青年项目，印度獐芽菜中[口山]酮调控整合素-FAK信号通路改善糖脂代谢的作用及机制研究，5万元，主持
3.中南民族大学中央高校基本科研业务费专项资金资助，獐牙菜苦苷促进骨骼肌鸢尾素分泌诱导白色脂肪棕色化治疗2型糖尿病的作用及机制，5万元，主持
4.国家自然科学基金面上项目，维吾尔药“欧帕日混”调控AMPK-GLUT4通路的抗糖尿病药效物质基础，48万元，参与
5.国家自然科学基金面上项目,脂肪组织细胞外基质重塑介导的整合素-FAK信号通路改变在肥胖发生中的作用及机制, 55万元,参与
发表论文
1.Yan Guo#,Huijian Chen#, Tongqing Li, Mi Huang, Pengxin Liu, Nabijan Mohammadtursun, Li Kang*, Ainiwaer Aikemu, Xinzhou Yang*. The liver kinase B1 mediates the therapeutic efficacy of nuciferine against hepatic lipid accumulation in diabetic KKAy mice. Phytomedicine 2026, 152: 157807.（中科院1区TOP)
2.Wenqi Liu, Minyu Chena, Sisi Wang, Shiwen Kang, Ni Zheng, Yerlan Bahetjan, Wenting Zhang*,Huijian Chen*, Xinzhou Yang*. Structurally diverse flavonoids from Selaginella doederleinii and their biological activity against laryngeal cancer. Chinese Journal of Natural Medicines2026, 24(4): 499-512.（中科院2区，IF 4.9）
3.Huijian Chen, Mi Huang, Maimaitijiang Abuduwake, Nabijan Mohammadtursun, Xinzhou Yang*. A review of the phytochemical and pharmacological properties of Flos Lonicerae Japonicae in treating obesity and type 2 diabetes mellitus: a medicinal and edible plant. Food, Nutrition and Health, 2025, 2:23.
4.Huijian Chen, Pengxin Liu, Xin Pan, Mi Huang, Tongqing Li, Yan Guo, Zongran Pang*, Nabijan Mohammadtursun, Xinzhou Yang*. Downregulation of collagen IV deposition and ITGB1-FAK signaling pathway to inhibit adipogenesis: A novel mechanism of swertiamarin in treating type 2 diabetes mellitus. International Journal of Biological Macromolecules, 2025, 299:140048.https://doi.org/10.1016/j.ijbiomac.2025.140048（中科院2区TOP）
5.Huijian Chen, Pengxin Liu, Ruitao Yu, Nabijan Mohammadtursun, Ainiwaer Aikemu*, Xinzhou Yang*, Swertiamarin ameliorates type 2 diabetes by activating ADRB3/UCP1 thermogenic signals in adipose tissue. Phytomedicine, 2024, 135:156190.（中科院1区TOP）
6.Tongqing Li#,Huijian Chen#, Yan Guo, Mi Huang, Pengxin Liu, Ainiwaer Aikemu, Nabijan Mohammadtursun, XinPan*, Xinzhou Yang*. Nuciferine restores autophagy via the PI3K-AKT-mTOR pathway to alleviate renal fibrosis in diabetic kidney disease. Journal of Agricultural and Food Chemistry, 2025, 73:5223-5235.（中科院1区TOP）
7.Hui-jian Chen; Xi-yue Yan; Ao Sun; Li Zhang; Jing Zhang; You-e Yan.Adiposeextracellular matrix deposition is an indicator of obesity and metabolic disorders, Journalof Nutritional Biochemistry, 2023, 111: 109159（中科院2区）
8.Huijian Chen, Xiyue Yan, Ao Sun, Li Zhang, Jing Zhang, Youe Yan *. High-fat-diet-induced extracellular matrix deposition regulates integrin – FAK signals in adipose tissue to promote obesity. Molecular Nutrition & Food Research, 2022, 66:e2101088.（中科院2区TOP）
9.HuijianChen,WanxiaZhang, Li Hu, Jie Fan, Li Zhang, Youe Yan*. Maternal nicotine exposure enhances adipose tissue angiogenic activity in offspring: Sex and age differences. Toxicology, 2020, 441:152506.（中科院2区）
10.HuijianChen, Gailing Li, Wanxia Zhang, Jie Fan, Li Hu, Li Zhang, Jing Zhang, Youe Yan*. Maternal nicotine exposure during pregnancy and lactation induces brown adipose tissue whitening in female offspring. Toxicology and Applied Pharmacology, 2020, 409:115298.（中科院2区）
11.Wanxia Zhang#,Huijian Chen#, Jie Fan, Gailing Li, Ao Sun, Liuyi Lan, Li Zhang, Youe Yan*. The association between maternal nicotine exposure and adipose angiogenesis in female rat offspring: A mechanism of adipose tissue function changes. Toxicology Letter,2020, 318:12-21.（中科院2区）
12.Huijian Chen, Gailing Li, Ao Sun, Dangsheng Peng, Wanxia Zhang, Youe Yan*. Age Differences in the Relationship between Secondhand Smoke Exposure and Risk of Metabolic Syndrome: A Meta-Analysis. International Journal of Environmental Research and Public Health, 2019, 16:1409.（中科院3区）
13.HuijianChen#,JieXiang#,WanxiaZhang,AoSun,GailingLi,YoueYan. Nicotine induces a dual effect on the beige-like phenotype in adipocytes. Archives of Biological Sciences. 2019, 71:533-540.（中科院4区）
其他任职
Journal of Agricultural and Food Chemistry、Science Bulletin、Advanced Science等期刊审稿人
湖北省中药活性物质国际合作基地 秘书
