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林显光
发布人:喻胜辉 发布时间:2015-03-25 浏览次数:

林显光 (Xianguang Lin)
出生年月日1980.02.27
汉族
副教授
学科专业生物医学工程
研究方向神经生物学
027-67841231
电子邮箱2012115@mail.scuec.edu.cn
简历(限600字以内。含毕业学校、学历学位、国外经历、社会学术团体兼职、荣誉称号、担任各类专家或学科组成员、研究领域介绍,承担项目、发表论文、专著、获奖、专利情况等)
毕业于华中科技大学生命科院,获生物物理专业博士学位,后在加拿大多伦多大学生理系进行博士后研究。主要领域为细胞分泌,蛋白质相互作用以及离子通道功能与疾病关联方面的研究。近年来发表多篇高质量论文,阐述了心脏病、糖尿病等相关的一些发病机理和分子机制,为将来彻底攻克这些疾病提供生物学基础。
近年代表性研究成果(限10项以内,含论文、专著、获奖、专利等)
  1. Liping Liao, Xianguang Lin, Jielin Hu, Xin Wu, XiaofeiYang, Wei Wang and Chenhong Li.SIMULATION AND CALCULATION OF THE CONTRIBUTIONOF HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS TO ACTIONPOTENTIALS.  Arch. Biol. Sci., Belgrade, 68(1),217-224, 2016. DOI: 10.2298/ABS150416144L

  2. Xie L, Liang T, Kang Y, Lin X, Sobbi R, Xie H, Chao C, Backx P, Feng ZP, Shyng SL, Gaisano HY.Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A toregulate cardiacATP-sensitive potassium (KATP) channels. J Mol Cell Cardiol. 2014Oct;75:100-10. doi: 10.1016/j.yjmcc

  3. Chao C, Liang T, Kang Y, Lin X, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A inhibits K(ATP) channels by interacting with specific conserved motifs within sulfonylurea receptor 2A. J Mol Cell Cardiol. 2011 Nov;51(5):790-802.

  4. Chang N, Liang T, Lin X, Kang Y, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A interacts with distinct domains within nucleotide-Binding folds of sulfonylurea receptor 1 to inhibit beta-cell KATP channels. J Biol Chem. 2011; May 3; 286(26):23308-18.

  5. Xian-Guang LIN, Min ming, Yang Xiao, Yaming Jiu, Maorong Chen, Zheng-Xing Wu and Tao Xu. UNC-31/CAPS docks and primes dense core vesicles in C. elegans neurons. Biochem Biophys Res Commun. 2010; Jul 2;397(3):526-31.

  6. Xian-Guang LIN, Recent Advance on Function of CAPS in Vesicular Exocytosis. Progress in Modern Biomedicine, 2010; Vol. 16.

  7. Dong Yong-Ming, ZHANG Ming, LIN Xian-Guang, ZHOU Wei, XIE Li, The Mechanism of Calcium Signaling Regulating Insulin Secretion. Progress in Modern Biomedicine, 2008; Vol. 8, No. 5, 937-939.

  8. ZHANG Ming, LIN Xian-Guang, JIU Yaming. The Mechanism of Extracellular SST Regulating Secretion of Insulin. JOURNAL OF HUAZHONG NORMAL UNIVERSITY ( Nat. Sci. ), 2008; June, Vol. 42, No.2, 256-261.

  9. Hao Zhang, Jie Luo, Jun Xiong, Xian-Guang Lin, Zheng-Xing Wu, Anlian Qu. Zf -and-Hsys-based Cm measurement under the whole-cell patch-clamp recording. Eur J Physiol 2009; 457:1423–1434.

  10. Ke-Ming Zhou, Yong-Ming Dong, Qian Ge, Dan Zhu, Wei Zhou, Xian-Guang Lin, Tao Liang, Zheng-Xing Wu, and Tao Xu. PKA Activation Bypasses the Requirement for UNC-31 in the Docking of Dense Core Vesicles from C. elegans Neurons. Neuron. 2007; November 21, 56, 657–669.

  11. Jie Liu, Qunfang Wan, Xian-Guang Lin, Hongliang Zhu, Kirill Volynski, Yuri Ushkaryov and Tao Xu. α-Latrotoxin Modulates the Secretory Machinery via Receptor-Mediated Activation of Protein Kinase C. Traffic 2005; 6: 756–765.

 

 

 

 

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